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The Deadly Duo You Need to Watch Out For, ETHealthworld

The Deadly Duo You Need to Watch Out For, ETHealthworld



“Diabetic? Your Heart May Already Be at Risk—Here’s What to Do”

In India and across the world, diabetes and cardiovascular disease (CVD) are rapidly emerging as two of the most serious public health challenges of our time. What makes them particularly dangerous is not just their individual impact, but the way they interact, amplify risk, and complicate each other’s management. Medical professionals often call this combination the “deadly duo”—and for good reason.


Dr. Smit Shrivastava, Interventional Cardiologist

Quotes:Heart disease is the leading silent killer for those over 40. Symptoms often go unnoticed until it’s too late. Make your check-ups non-negotiable and your wellness a daily priority. Your heart isn’t just pumping blood-it’s powering your life.

Diabetes Increases Heart Disease Risk Dramatically

People living with Type 2 Diabetes Mellitus (T2DM) are significantly more prone to developing heart disease than the general population. In fact, diabetes doubles to quadruples the risk of atherosclerotic cardiovascular disease (ASCVD), which includes heart attacks, strokes, and peripheral artery disease.

The reason lies in how elevated blood glucose damages blood vessels over time. Chronic hyperglycemia leads to inflammation, endothelial dysfunction, and increased cholesterol deposition in arteries—all of which accelerate the process of atherosclerosis, or plaque buildup.

Thus, for someone with diabetes, even in the absence of traditional symptoms, heart disease risk is always lurking in the background.

Dr. Sanchita Mazumdar, Interventional Cardiologist

Quote: Turning 40 is not a health decline-it’s a wake-up call. Your heart has been working hard for decades. Support it with healthy habits, manage stress, and never ignore signs like fatigue or chest discomfort. Prevention begins with awareness

Why This Combination Is So Dangerous

When diabetes and heart disease coexist, each condition exacerbates the other. Diabetes not only increases the risk of heart disease but also makes its onset earlier, more severe, and harder to manage. Diabetic patients often experience silent heart attacks—episodes that go unnoticed until they have caused significant damage.

Moreover, once cardiovascular disease is established, managing diabetes becomes more complicated. Fluctuating glucose levels, medication interactions, and compromised organ function can make both diseases spiral out of control if not carefully monitored and treated.

Dr. Deepankar Vatse, Interventional Cardiologist
Quote: Many heart attacks happen without warning-but most are preventable. After 40, consider your lifestyle as medicine. Daily walks, mindful eating, less sugar, and annual heart checkups are your strongest protection against one of the most preventable diseases.

Time to Intervene Early—Starting at Age 40

One of the strongest lessons emerging from clinical guidelines and cardiovascular studies is this: don’t wait for symptoms to show up. Instead, adopt a preventive approach—starting early, especially at age 40.

Medical guidelines now recommend that individuals with Type 2 diabetes undergo risk evaluation for cardiovascular disease by age 40, and in many cases, begin preventive treatment strategies. These may include medications that lower cholesterol, such as statins, alongside lifestyle modifications, to reduce the risk of first-time cardiovascular events.

It’s important to note that this recommendation applies even in patients without any previous heart complications. The goal is to reduce risk before the first event happens—not after.

Not Just Sugar: LDL-C and Blood Pressure Also Matter

In managing diabetes, glucose control is only one part of the equation. Other risk factors like high LDL cholesterol (LDL-C) and hypertension must be addressed aggressively. Studies have shown that LDL-C contributes significantly to atherosclerosis in diabetics. Similarly, blood pressure targets in diabetic individuals must be tighter to prevent stroke and heart failure.

Dr. Ashwin Kumar Panda, Consultant Interventional Cardiologist

Quote: Metabolic syndrome, seen frequently in urban Indian adults post-40, significantly increases the risk of heart attacks. Waist size, fasting glucose, HDL, and triglycerides are crucial markers. Routine health checks can help manage these before complications set in.

Yet, despite these known risks, many patients and even some healthcare systems focus exclusively on glucose, often overlooking these silent but critical contributors to cardiovascular disease. A comprehensive, multi-factorial approach is the need of the hour.

Empowering Patients with Awareness

Diabetic patients often undergo routine glucose monitoring, but they must also be educated about their heightened cardiovascular risk. Simple lifestyle changes—daily walking, smoking cessation, dietary adjustments, and stress control—can offer powerful protection.

Equally, understanding lab reports, LDL-C goals, and blood pressure readings can empower patients to be active participants in their care. The earlier they begin, the greater the benefit.

Dr. Girish G, Senior Consultant Interventional Cardiology

Quote: Indians develop heart disease nearly a decade earlier than Western populations. After 40, monitor cholesterol, blood sugar, and blood pressure regularly. A sedentary lifestyle, high-carb diet, and stress only accelerate cardiovascular risk. Prevention starts with awareness and regular health checkups.

Conclusion: One Disease Often Leads to Another—Unless You Act

Diabetes and heart disease don’t operate in silos. They are deeply interconnected, and tackling one without addressing the other is a missed opportunity for prevention. The 40s are a turning point, especially for those living with diabetes. This is the right time to evaluate cardiovascular risk and begin proactive treatment strategies, even if you feel “fine.”

The deadly duo doesn’t have to be inevitable. With early action, goal-driven care, and regular monitoring, it’s possible to not just manage diabetes but also prevent it from taking your heart down with it.

Disclaimer – The above content is non-editorial, and ET Healthworld hereby disclaims any and all warranties, expressed or implied, relating to it, and does not guarantee, vouch for or necessarily endorse any of the content.

  • Published On Jul 25, 2025 at 05:29 PM IST

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