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Lucknow: Genetic and pathological foundation of isolated congenital heart defects (ICHD), the leading type of heart malformation found in newborns, is still not well understood, though modern diagnostic tools allow early detection and possible medical intervention or pregnancy termination.
A research initiative of stem cell research centre under department of hematology at SGPGIMS seeks to bridge this knowledge gap by investigating molecular and genetic basis of ICHD.
“Insights could lead to better prevention strategies and improved treatments,” said Dr Chandra Prakash Chaturvedi, whose team secured Rs 4.18 crore grant from Indian Council of Medical Research.
Dr Chaturvedi said the project aimed to save young lives. By pinpointing molecular patterns related to isolated congenital heart defects, researchers hope to clarify biological mechanisms, identify crucial genes and protein markers and discover new targets for early diagnosis and regenerative therapies.
Aim is to find early detection biomarkers and pioneer treatments to transform care of newborns with ICHD, ensuring healthier pregnancies.
Professors Mandakini Pradhan and Neeta Singh from department of maternal and reproductive health at SGPGIMS will act as co-principal Investigators.
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